Download Chemical Modulators of Protein Misfolding and by Pierfausto Seneci PDF

By Pierfausto Seneci

This publication is a neurochemistry-based significant other for Protein Misfolding and Neurodegenerative ailments: Molecular Targets, an Elsevier identify by means of a similar writer publishing in December 2014. whereas the 1st ebook makes a speciality of biology and molecular goals, this better half booklet describes how those goals are regulated by means of small molecules and disease-modifying compounds. The ebook starts with a short advent to how key proteins turn into dysfunctional, and every next bankruptcy describes significant affliction mechanisms in Alzheimer’s and different tauopathies. homes and improvement prestige of those molecular goals and ailment mechanisms are completely defined, as are small molecule effectors of autophagy and dis-aggregating brokers.

  • Written to supply entire insurance of neurodegenerative disease-modifying compounds
  • Provides discipline-specific chapters that disguise medicinal chemistry and scientific applications
  • Provides an outline of greater than two hundred chemical sessions and lead compounds, performing on chosen molecular goals which are of relevance to any neurodegenerative disorder
  • Coverage of misfolding ailments, chaperone proteins, ubiquitination and autophagy/oncology makes this e-book appropriate for structural neurochemists, chemists, biologists, non-CNS scientists, and scientists drawn to drug discovery

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